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56 year old man presents to the ER with complaints of abdominal pain and mild headache. Also has recent onset of trouble concentrating.
PE is non-contributory
A Lumbar puncture was performed and CSF analysis is positive
• Subtle increase in T2 signal within the midbrain surrounding the red nuclei and involving the substantia nigra
• No mass effect nor pathologic enhancement.
• Demyelinating disease
» ADEM
» Multiple Sclerosis
• Ischemia or Infarction
• Encephalitis
Dx: West Nile Encephalitis
Dx Confirmed by: CSF serology with positive PCR for West Nile Infection
Antiviral chemotherapy
West Nile Encephalitis was catapulted to National attention in the Summer of 2001, and has become a major problem since 2002. In the Summer of 2012, there was a significant increase in reported cases. In Texas, Governor Rick Perry ordered aerial spraying for mosquitos - which has not been done for decades.
CDC on West Nile - - LINK -
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