MedPix® Patient Chart - Case No: 4153 :: Imaging - Review Images

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History

Age: 43 :: Gender: man

Patient History

Postal worker with flu-like symptoms.

Exam


Physical Exam and Laboratory

Specific exam and lab values were not avaiable.


Findings


Summary of Findings

Chest Radiograph, Patient A, Day 4: Widened mediastinum with medistinal adenopathy, hilar fullness and small bilateral pleural effusions.

CT (noncontrast), Patient A, Day 4: Confirmed the hilar and mediastinal adenopathy, particularly subcarinal adenopathy, and small bilateral pleural effusions.


CT (IV contrast), Patient A, Day 5: Interval enlargement of the adenopathy and increased pleural effusion to approximately 60% of his chest volume. With the use of IV contrast in this study, the adenopathy shows enhancement and the central necrotic center is well demonstrated consistent with hemorrhagic adenpathy.


Diffferential


Differential Diagnosis

Malignant neoplasm
Aggressive Infection


Diagnosis


Case Diagnosis

Dx: Inhalation Anthrax


Dx Confirmed by:

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Followup


Followup and Treatment

Both patients recieved IV antibiotic therapy.

Discussion


Discussion for this Patient

Two patients presented 4 days after exposure to inhalation anthrax. Inital examinations demponstrated massive medistinal adenopathy and small bilateral pleural effusions. The follow up CT examination on Patient A demonstrates enlargement of the adenopathy and increased pleural effusion to approximately 60% of the chest volume. With the use of IV contrast in this study, the adenopathy shows enhancement and the central necrotic region is well demonstrated - consistent with hemorrhagic adenpathy. This patient also had airspace disease which is non specific. However, in autopsy cases inhalation anthrax was shown to have focal hemorrhagic necrotizing pneumonic lesions.


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History:
Postal worker with flu-like symptoms.

Exam:
Specific exam and lab values were not avaiable.

Findings:
Chest Radiograph, Patient A, Day 4: Widened mediastinum with medistinal adenopathy, hilar fullness and small bilateral pleural effusions.

CT (noncontrast), Patient A, Day 4: Confirmed the hilar and mediastinal adenopathy, particularly subcarinal adenopathy, and small bilateral pleural effusions.


CT (IV contrast), Patient A, Day 5: Interval enlargement of the adenopathy and increased pleural effusion to approximately 60% of his chest volume. With the use of IV contrast in this study, the adenopathy shows enhancement and the central necrotic center is well demonstrated consistent with hemorrhagic adenpathy.



Differential:
Malignant neoplasm
Aggressive Infection

Diagnosis:
Inhalation Anthrax
Confirmed by:

Treatment and Followup:
Both patients recieved IV antibiotic therapy.

Discussion:
Two patients presented 4 days after exposure to inhalation anthrax. Inital examinations demponstrated massive medistinal adenopathy and small bilateral pleural effusions. The follow up CT examination on Patient A demonstrates enlargement of the adenopathy and increased pleural effusion to approximately 60% of the chest volume. With the use of IV contrast in this study, the adenopathy shows enhancement and the central necrotic region is well demonstrated - consistent with hemorrhagic adenpathy. This patient also had airspace disease which is non specific. However, in autopsy cases inhalation anthrax was shown to have focal hemorrhagic necrotizing pneumonic lesions.

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Case Contributor and Editor

Submitted by: Maria Flynn - Author Info
Case/Image Editor: - Editor Info
Case Accepted: :: Revised: :: Submitted:
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