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TitleArnold-Chiari Malformations
TextChiari Malformations (CM) are divided into 4 subtypes.

• CM - 1 is diagnosed by appropriate symptoms and low lying cerebellar tonsils (cerebellar tonsillar ectopia - tonsils > 5mm below foramen magnum). The phsyiology is not related to the degree of hernation, but rather to the CSF flow around the tonsils. Symptoms include:
» Decreased sensation/numbness in extremities
» Upper extremity pain, weakness
» Headache
» Tinnitus
» Decreased facial sensation (spinal portion of CNN V)
» Gait disorder, bowel/bladder Sx, Nystagmus
NOTE: Patients may be symptomatic with only 3mm of herniation; and, asymptomatic with up to 10 mm. Syringohydromyelia is associated in 20-25%.

• CM - 2 Is like CM-1, but includes a spinal dysraphism (myelomeningocele). This is the "Arnold-Chiari" malformation. The posterior fossa may be small, and both the cerebellum and 4th ventricle are herniated through the Foramen Magnum, usually with "kinking" of the medulla and/or cervical cord (up to 70%). These patients usually have a complex malformation including hydrocephalus, a "beaked" midbrain, callosal anomalies (up to 90%, such as agenesis of the rostrum and or splenium.

• CM - 3 Chiari III malformation is like a CM - 2, but includes a cervical/occipital encephalocele.

• CM - 4 Chiari IV is controversial and not accepted by all authors. It is a small or underdeveloped cerebellum.
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http://www.pressenter.com/~wacma/milhorat.htm

http://cpmcnet.columbia.edu/dept/nsg/PNS/ChiariMalformation.html

http://rad.usuhs.mil/rad/home/spine/davospine.html
References:
ContributorJames George Smirniotopoulos, M.D. (Uniformed Services University)
Peer ReviewerJames G. Smirniotopoulos, M.D. (Uniformed Services University)
Record Number : 436
Created1998-01-28 00:00:00-05
Modified2007-03-16 15:14:27-04
Category:Congenital, malformation
Location:Brain and Neuro
Sublocation:Posterior Fossa
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