|Print Date:||May 23, 2013, 2:52 am|
|Text||Synonyms: Cystosarcoma Phyllodes
Associations/Predisposing Factors: None
Clinical: 0.3% of all breast tumors. Closely resembles fibroadenomas, both radiographically and histologically. A palpable mass is frequently noted.
Demographics: Patients are typically 15-20 years older (mean age in mid-40s) than women with fibroadenomas.
Gross: Tan, gray or yellow with cystic and gelatinous portions often seen. Leaflike processes protrude into cystic spaces (hence its name Phyllodes which is Greek for leaf-like).
Histology: Benign epithelial elements and a cellular stroma. Differentiation from fibroadenoma is subjective, based upon estimation of stromal cellularity and the presence of leaf-like processes projecting into cystic spaces. Differentiation of low and high grade tumors is based upon infiltrative growth, moderate-to-severe atypia, and three or more mitotic figures per x10 high-power field.
Radiology: Mammography depicts a well-circumscribed mass. US shows a hypoechoic, well-circumscribed mass with increased thru transmission often seen.
Treatment: Surgical excision.
|References:||Cardenosa G. Lobules. in Breast Imaging Companion, 2d Ed. Lippincott Williams & Wilkins, Philadelphia PA, p292|
|Contributor||Kevin Banks (Brooke Army Medical Center)|
|Peer Reviewer||Thomas M. Dykes (Penn State University)|
|Record Number||: 5263|
|Location:||Breast and Mammography|
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