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Print Date: May 23, 2013, 12:09 pm
TitleOrbital lymphoma, Extraconal masses
TextDifferential diagnosis for masses in the superolateral quadrant of the orbit include:

Lymphoma
Pseudotumor
Lacrimal gland or duct tumor
Dermoid cyst
Metastasis
Hemangioma
Schannoma or Neurofibroma
Saroidosis

Orbital lymphoma is the third most common cause of unilateral proptosis, following pseudotumor and orbital hemangioma. Non-Hodgkin B cell is the most common type.

Lymphoma tends to surround adjacent structures, without eroding bone, and most lie anterior and superior in the orbit, in close proximity to the lacrimal gland. However, any area of the orbit may be involved.

Presenting sympoms often include painless eyes swelling, proptosis, oculomotor/visual acuity defects.

If there is no systemic involvement, orbital lymphomas are typically treated with local radiation. Chemotherapy is used in cases of systemic invovement.

Classic cross-section image findings include:
» CT: hyperdense mass that is well demarcated as compared to the hypodense orbital fat and enhancement with contrast.

» MR: hypointense / isointense compared to hyperintense fat tissue on T1- and T2-weighted images respectively. Mild enhancement is usually demonstrated



References:Harnsberger R. Head and Neck Imaging. Mosby, St. Louis; 1990:370-371

Flanders AE. Orbital Lymphoma Role of CT and MRI.
Radiologic Clinics of North America. 1987;25:601-612

www.amershamhealth.com
ContributorPaul M Michaud (Walter Reed Army Medical Center)
Peer ReviewerJames G. Smirniotopoulos, M.D. (Uniformed Services University)
Record Number : 6833
Created2005-11-06 21:36:20-05
Modified2005-11-07 05:36:11.827279-05
Category:Neoplasm, hematopoietic
Location:Eye and Orbit (exclude Ophthalmology)
Sublocation:Extraconal
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