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TitleOrbital Nodular Fasciitis
TextNodular fasciitis is a benign proliferative lesion, which may resemble a sarcoma - because of its rapid growth and lack of associated infection. Pathologically it has high mitotic activity, high cellularity, and infiltrative growth pattern.

Most commonly, it arises in the upper extremities, followed by the head and neck region, lower extremities, and finally the trunk. Most cases reveal a rubbery-hard consistency mass that is mobile and non-tender.

On both CT and MR, the lesion is usually well circumscribed if in the soft tissues; and, more infiltrative in nature if arising in the deep musculature. While nodular fasciitis is benign, the deeper seated lesions may exhibit aggressive features, destroying adjacent structures including bone.

No one defining enhancement pattern (on CT or MR) or signal intensity is characteristic.
References:Kim ST, Kim HJ, Park SW, et al. Nodular fasciitis in the Head and Neck: CT and MR Imaging Findings. AJNR 26:2617-2623. November/December 2005.
ContributorJason W. Schroeder (Civilian Medical Center)
Peer ReviewerJames G. Smirniotopoulos, M.D. (Uniformed Services University)
Record Number : 8863
Created2008-09-06 14:38:32-04
Modified2008-09-07 09:02:07.773742-04
Category:Inflammatory, NOS
Location:Eye and Orbit (exclude Ophthalmology)
Sublocation:None Selected
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