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Question 1

1) Which of these is not associated with abnormal iron deposition and T2/T2* hypointensity in the globus pallidus?
  1. pantothenate kinase 2 mutation (PANK2)
  2. aceruloplasminemia
  3. Infantile neuroaxonal dystrophy
  4. Neuroferritinopathy
  5. Wilson disease
Answer Resources: - [PubMed] || [ WEB ] -
Question by: James G. Smirniotopoulos, M.D. - Author Info

Approved by: James G. Smirniotopoulos, M.D.
Errors: None
Question 2

2) Which of these disorders has the highest penetrance for the "eye of the tiger" sign?
  1. pantothenate kinase 2 mutation (PANK2)
  2. Hallervorden-Spatz (HS) without PANK2
  3. Infantile neuroaxonal dystrophy
  4. aceruloplasminemia
  5. ferritinopathy
Answer Resources: - [PubMed] - [PubMed] || [ WEB ] -
Question by: James G. Smirniotopoulos, M.D. - Author Info

Approved by: James G. Smirniotopoulos, M.D.
Errors: None
Question 3

3) Which of these is not a feature of PKAN (PANK2 or NBIA-1)
  1. Parkinsonism
  2. Rigidity
  3. Hyperreflexia
  4. Giant panda sign
  5. Dystonia
Answer Resources: - [PubMed] - [PubMed] || [ WEB ] - [ WEB ] -
Question by: James G. Smirniotopoulos, M.D. - Author Info

Approved by: James G. Smirniotopoulos, M.D.
Errors: None
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