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Terms not used: | Search Results for => Leigh <= Result Items 1 - 20 |
| Case ID: 11420 Sample Image  Click to View  | ::  - TF Case ::  - Thumbnails ::  - Topic
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| Diagnosis | Leigh's disease (subacute necrotizing encephalopathy). | |
| History | A 2 month old male with mental status changes for evaluation with a non-contrast head CT. | |
| Findings | On CT, there is marked and diffuse volume loss, ex vacuole dilatation of the ventricles, and cystic changes of the basal ganglia, cerebellum and thalami. Follow-up MR again reveals diffuse parenchymal atrophy with cystic degeneration of cerebellum, cerebral peduncles, thalami and the basal ganglia. On spectroscopy, there is a significant depression of the NAA peak with a resultant increase in the choline peak. Lactate is also present. | |
| Differential Dx | Profound perinatal asphyxia Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) Glutaric aciduria type I Wilson disease | |
| Discussion | ... (continues ...) | |
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| Contributor | Michael J Reiter :: National Capital Consortium -  | |
| Reviewer | Alice Boyd Smith :: Uniformed Services University - Case Accepted: 2007-11-07 16:36:48-05 :: Revised: :: Submitted: | |
| Case ID: 10730 Sample Image  Click to View | :: - TF Case :: - Thumbnails :: - Topic
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| Diagnosis | Leigh's disease (subacute necrotizing encephalopathy). | |
| History | 16 year old male diagnosed with pyruvate dehydrogenase deficiency at age 5. Presents with respiratory failure and coma | |
| Findings | Lesions in the upper cord, medulla, brainstem, and basal ganglia. The basal ganglionic lesions enhance following contrast administration. | |
| Differential Dx | Cerebral ichemia Demylinating disease Toxic encephalopathy | |
| Discussion | ... (continues ...) | |
| User Group | ||
| Contributor | Steven J Goldstein :: University of Kentucky - | |
| Reviewer | Steven J Goldstein :: University of Kentucky - Case Accepted: 2007-11-07 16:36:48-05 :: Revised: :: Submitted: | |
| Case ID: 2228 Sample Image  Click to View | :: - TF Case :: - Thumbnails :: - Topic
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| Diagnosis | Leigh disease | |
| History | ||
| Findings | ||
| Differential Dx | ||
| Discussion | ... (continues ...) | |
| User Group | ||
| Contributor | James G. Smirniotopoulos, M.D. :: Uniformed Services University - | |
| Reviewer | :: - Case Accepted: 2007-11-07 16:36:48-05 :: Revised: :: Submitted: | |
| 3 Search Results for => Leigh <= Result Items 1 - 20 |
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