Pituitary adenomas are the most common intrasellar masses.

Microadenomas are those that are less than or equal to 10 mm in size, and macroadenomas are those that are greater than 10mm. Seventy-five percent of adenomas are microadenomas.

Prolactin and ACTH secreting tumors are more common, even in males.
Microadenomas are discovered while they are small due to endocrine symptoms.

Macroadenomas most commonly present secondary to mass effect, with symptoms related to optic nerve/chiasm compression, hydrocephalus, cranial nerve palsies, or occasionally anterior pituitary dysfunction.

Clivus or cavernous sinus invasion generally precludes complete surgical resection.