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MedPix® Medical Image DatabaseDisease Topic 1464
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Contributor: Grady Shue - National Capital Consortium
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More Like This ? Toxoplasmosis
Factoid 1464 - Created: 2001-03-23 14:12:48-05 - Modified: 2006-08-08 18:23:04-04
ACR Codes: 1.2
Toxoplasmosis gondii is an obligate intracellular protozoan parasite. Infection is due to ingestion of undercooked meat containing cysts or sporulated oocysts, transplacental transmission of trophozoites, or acquired through blood transfusion/organ transplantation. The organism affects the brain, retina, lungs, skeletal muscle, and heart.

In AIDS patients, the infection inovlves the basal ganglia (75%) and/or is scattered throughout the brain parenchyma at the gray-white junction. Approximately 40% of infections are solitary. Lesions demonstrate ring enhancement and surrounding edema. There is improvement with medical therapy. The differential diagnosis includes CNS lymphoma, especially if there is a single lesion.

Intrauterine infection demonstrates increased risk of placental transmission late in pregnancy. Chorioretinitis and mental retardation are common sequelae. Microcephaly is not present. Periventricular and choroid calcifications are a common feature.
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Location:
Brain and Neuro 		Sublocation:
Basal Ganglia		Category:
Infection, parasite
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Prepared by: Grady Shue
Affiliation: National Capital Consortium - || - Author Profile
Approved by: James G. Smirniotopoulos, M.D.
Affiliation: Uniformed Services University - || - Editor Profile
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