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MedPix® Medical Image DatabaseDisease Topic 2270
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Contributor: Aaron Auerbach - Walter Reed Army Medical Center
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More Like This ? Oligodendroglioma
Factoid 2270 - Created: 2001-06-26 14:22:16-04 - Modified: 2001-09-27 10:34:57-04
ACR Codes: 1.3
Definition: A well-differentiated, diffusely infiltrating tumor of adults, typically located in the cerebral hemispheres and composed predominantly of cells morphologically resembling oligodendroglia.

Oligodendrogliomas are composed of cells with round homogenous nuclei and abundant clear cytoplasm. Classically, these have been described as "fried eggs." A dense network of capillaries is common. The branching of the capillaries resemble the pattern of chicken wire. Microcystic degeneration and microcalcifications are common.

Immunohistochemistry: There is no immunocytochemical marker which is specific for ligodendroglial tumor cells. These cells are often positive for S-100, Leu-7 and GFAP.
Reference(s):
WHO Classifications of Tumours: Tumours of the Nervous System, 2001.
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Brain and Neuro 		Sublocation:
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Neoplasm, glial
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Prepared by: Aaron Auerbach
Affiliation: Walter Reed Army Medical Center - || - Author Profile
Approved by: James G. Smirniotopoulos, M.D.
Affiliation: Uniformed Services University - || - Editor Profile
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