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Contributor: James G. Smirniotopoulos, M.D. - Uniformed Services University
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More Like This ? Pseudotumor cerebri (idiopathic intracranial hypertension)
Factoid 433 - Created: 1998-01-26 00:00:00-05 - Modified: 2009-10-29 06:09:14-04
ACR Codes: 1.3
Increased intracranial pressure - not produced by an expansile mass lesion - if often called "pseudotumor cerebri". Reported by Heinrich Quincke in 1893 and by Max Nonne in 1904, it was originally called "serous meningitis". It is most common in overweight women 20-50 years old. The presentation is with headaches or visual problems.

The diagnostic criteria include:
• secondary features of increased pressure (e.g. papilledema)
• elevated CSF pressure (>250 mm H2O) by LP in lateral decubitus position
• normal cerebrospinal fluid chemistry and cells
• normal cerebral anatomy by CT/MR imaging

LP Results:
• http://www.aafp.org/afp/20030915/1103.html
• http://www.fpnotebook.com/Neuro/Lab/CrbrspnlFldExmntn.htm
• http://www.ncbi.nlm.nih.gov/pubmed/19515130

Increased intracranial pressure, but without a focal tumor (hence "pseudotumor"). Usually described as "idiopathic" there are multiple possible causes:
• cerebral edema
• hyperemic swelling
• imbalance between CSF production and resorption
• venous hypertension, dural sinus stenosis (including bilateral transverse sinus stenosis - PMID: 19515130 http://www.ncbi.nlm.nih.gov/pubmed/19515130


http://www.ninds.nih.gov/disorders/pseudotumorcerebri/pseudotumorcerebri.htm

http://www.mayoclinic.com/health/pseudotumor-cerebri/DS00851

http://www.webmd.com/brain/pseudotumor-cerebri-10678

http://emedicine.medscape.com/article/1143167-overview

http://www.revoptom.com/HANDBOOK/SECT53a.HTM

http://en.wikipedia.org/wiki/Idiopathic_intracranial_hypertension
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Prepared by: James G. Smirniotopoulos, M.D.
Affiliation: Uniformed Services University - || - Author Profile
Approved by: James G. Smirniotopoulos, M.D.
Affiliation: Uniformed Services University - || - Editor Profile
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