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MedPix® Medical Image DatabaseDisease Topic 635
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Contributor: James George Smirniotopoulos, M.D. - Uniformed Services University
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More Like This ? Oligodendroglioma
Factoid 635 - Created: 1999-01-14 00:00:00-05 - Modified: 2001-09-27 12:20:20-04
ACR Codes: 1.3
79 patients with 'pure' oligodendroglioma, 52% had adequate follow-up. Contrast enhancement and endothelial hyperplasia correlated with survival:
Median survival:
11 years w/o enhancement and 11 yrs w/o endothelial
Only 3 years w/enhancement and 3.5 yrs w/endothelial prolif
Conversely, nuclear atypia, necrosis, mitosis were not correlated with survival.

New Oligodendroglioma grading system developed:
Grade A - absence of endothelial hyperplasia, non-enhancing
Grade B - with endothlial hyperplasia and/or enhancing
Survival for Grade A: 89% at 5yrs/ 60% at 8 yrs
Survival for Grade B: 33% at 5yrs/ 15% at 8 yrs

Double-blind grading was concordant in 96% of cases.

DaumasDuport97
J Neurooncol 1997;34:61-78
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Neoplasm, glial
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Prepared by: James George Smirniotopoulos, M.D.
Affiliation: Uniformed Services University - || - Author Profile
Approved by: James G. Smirniotopoulos, M.D.
Affiliation: Uniformed Services University - || - Editor Profile
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