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MedPix® Medical Image DatabaseDisease Topic 882
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Contributor: James G. Smirniotopoulos, M.D. - Uniformed Services University
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More Like This ? Pineal Region Masses, Pineal parenchymal tumors
Factoid 882 - Created: 1997-01-01 14:53:50-05 - Modified: 2009-09-23 11:13:26-04
ACR Codes: 1.3
The vast majority of masses in the pineal region are germ cell tumors, most commonly "germinomas". These masses were originally called "pinealomas" because of their location. In 1952 Neuropathologist Dorothy Russell recognized that many of these masses were similar to testicular seminomas (also called germinoma, dysgerminoma, or atypical teratoma).

Most patients with intracranial germ cell tumors are young males, who may have regional sympotoms and signs sucha as Parinaud syndrome and precocious puberty. Other patients may have non-localizing findings like headache and hydrocephalus.

http://theoncologist.alphamedpress.org/cgi/content/full/5/4/312
http://en.wikipedia.org/wiki/Germ_cell_tumor
http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970236-4
http://journals.lww.com/jneuropath/Abstract/1985/01000/Intracranial_Germ_Cell_Tumors__Pathobiological_and.3.aspx

• Pineal Region Germ Cell tumors
• Germinoma
• Teratoma
• Endodermal sinus (yolk sac tumor)
•


PMID: 19636276
PMID: 19588227
PMID: 19329863

• Pineal Parenchymal Tumors

The WHO also recognized these tumors of the pineal parenchyma:
• ICD-0 9361/1 Pineocytoma (WHO grade 1)
• ICD-0 9362/3 Pineal parenchymal tumor w/intermediate differentiation (WHO 2 or 3) PMID: 18266015
• ICD-0 9362/3 Pineoblastoma (WHO grade 4)
• ICD-0 9395/3 Papillary tumor of Pineal Region (WHO 2,3)

PMID: 19373436
Reference(s):
; Accepted by jsmirnio
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Location:
Brain and Neuro 		Sublocation:
Pineal Region		Category:
Neoplasm, non-glial
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Prepared by: James G. Smirniotopoulos, M.D.
Affiliation: Uniformed Services University - || - Author Profile
Approved by: Alice Boyd Smith
Affiliation: Uniformed Services University - || - Editor Profile
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