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Sickle Cell Anemia, MedPix™ : 1020 - Medical Image Database and Atlas
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More Like This ? Hematopoietic
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More Like This ? Congenital, genetic
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TOPIC and DISCUSSION :: Slide Sorter :: Print Topic :: Slide Sorter ::

More Like This ? Sickle Cell Anemia
Topic 1020 - Created: 2000-09-09 07:09:47-04 - Modified: 2004-04-25 04:17:39-04
ACR Index: 4.6

Sickle cell anemia (SCA) is an inherited hemogloblinopathy. Pts who are homozyogous have complications related to both the anemia and to repeated thrombotic vaso-occlusive episodes and hemolysis.

Modern treatment has made a significant improvement in prognosis. In the early '70's, mean age at death was around 14 years old. In 1994 a study of almost 4k pts showed survival into the 40's for SCA, and twenty years longer for HbSC disease.

Organ failures due to vaso-occlusion includes spleen ("auto-splenectomy"), kidney, lung, and brain. Treatment is aimed at minimizing both the frequency and the severity of the vaso-occlusive episodes of "sickle cell crisis".

Extramedullary hematopoiesis

Bone Changes

Treatment of SSA:
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General Websites about SCD:
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More About SCD:
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What causes the hemoglobinopathy:
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Contributor Credits

Submitted by: James G. Smirniotopoulos, M.D. - Author Info
Affiliation: Uniformed Services University
Approved By: James G. Smirniotopoulos, M.D. - Editor Info
Affiliation: Uniformed Services University


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