Lesion/Condition Name: Pancreatic Mucinous Cystadenoma.

What is it? Neoplasm - cystic adenoma of the pancreas. Often benign but has malignant potential.

Cell of Origin: Columnar epithelial cells.

Synonyms: Mucinous cystic neoplasm.

Common Locations: Body or tail of pancreas.

Description: Mucinous cystadenomas are the most common cystic pancreatic neoplasms accounting for approximately 10% of pancreatic cysts. Cystic neoplasms make up less than 1% of all pancreatic neoplasms, most being adenocarcinomas.
Mucinous cystadenomas occur most often in middle age women. Mean age 50 years old. 50% occur between 40-60 years of age. M:F 1:19.

Gross Morphology: Macrocystic mass, can have thick irregular walls and septa. Peripheral or septal calcifications.

Gross Appearance: Multiloculated cysts filled with thick mucinous material.

Histology: Columnar mucinous epithelium, dense stroma.

Radiology: CT shows unilocular or multilocular macrocystic appearance. They can have peripheral or septal calcification in 20% of cases. Mucinous cystadenoma's typically show contrast enhancement.

Prognosis and Treatment: Mucinous cystadenomas can be benign or malignant and can undergo
malignant transformation. Histopathology is necessary for definitive diagnosis. Prognosis
is generally good if there is no evidence of distant metastasis. Treatment is surgical
resection. 5 year survival is 74-90%.