Discussion Author: Seth D. O'Brien
Erosive osteoarthritis is a variant of osteoarthritis that has exactly the same distribution in the hands. This condition typically affects postmenopausal females for reasons unknown. Sites of involvement are the distal interphalangeal and proximal interphalangeal joints as well as the 1st carpometacarpal joint and greater multangular-navicular joint in the wrist.
Erosive osteoarthritis shares the same distribution as "regular" osteoarthritis, and also shares features such as subchondral sclerosis, joint space narrowing and osteophyte formation. What distinguishes erosive osteoarthritis is that there is an inflammatory component of the disease which classically produces central erosions.
The main differential diagnosis is psoriasis which can have the same distribution of disease, however in psoriasis the erosions are peripheral, one can see periostitis, and there is no osteophyte formation.

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