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Clinical Presentation: 12 y.o. girl

History

12 girl with incidental finding on barium upper GI examination. Patient is asymptomatic with respect to any chest complaints.

Physical Examination and Laboratory

Noncontributory.

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Image Findings

Frontal and lateral views of the chest show a mass which, on the frontal view, is at the right paramediastinal area and shows very clearly demarcated convex lateral margin. The aortic edge and right paratracheal stripe are preserved, suggesting a posterior location of the mass. No peripheral lung changes are present. On lateral view, very subtle increased opacity is seen over the upper thoracic spine.

Selected axial CT images of the chest show a non-aggressive appearing cystic mass at the posterior mediastinum on the right side, consistent with congenital respiratory cyst. Other etiologies to consider would be enteric cyst and neurogenic cyst.

ADDENDUM: Following biopsy obtained after this case was originally submitted to MEDPIX, histology revealed a diagnosis of ganglioneuroma.

Differential Diagnosis

Bronchopulmonary foregut malformation
Enteric cyst
Neurogenic cyst
Neurogenic neoplasm

Diagnosis

Ganglioneuroma :: Diagnosis Topic Read Topic
Diagnosis Confirmed by: Biopsy histology was ganglioneuroma.

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Treatment and Followup

Tx and Followup:
ADDENDUM: Following biopsy obtained after this case was originally submitted to MEDPIX, histology revealed a diagnosis of ganglioneuroma.

Additional Discussion:
Please see factoid.

Topic Discussion

Discussion Author: James George Smirniotopoulos, M.D.

Zulch refutes this term, replacing it with "gangliocytoma". Rubinstein [Russell and Rubinstein]: the neoplastic neurons are supported by capsular cells, abundant schwannian and connective tissue. "If ... name 'ganglioneuroma' ... includes the neuromatous component, then it is, stricly speaking, a misnomer when applied to its counterpart in the CNS."

THORACIC More common in the posterior mediastinum than any other single location, about 20-40% of post mediastinal masses.

ABDOMINAL taken as a whole has more, but they may be mesenteric, intestinal, or paraspinal

SPINAL almost always with a "substantial extraspinal moiety arising from the sympathetic chain"

Diagnosis Topic Topic Details: Ganglioneuroma :: :: Search for other Topics with Ganglioneuroma

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Contributor Credits

Topic Author: James George Smirniotopoulos, M.D.
Submitted by: Jason Rexroad -
Affiliation: Civilian Medical Center
Approved By: Albert V Porambo -

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-2 :: Case - 7353 :: Medical Image Database, Atlas, and Teaching File All Cases are Peer Reviewed by an Editoral Panel

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Clinical Presentation: 12 y.o. girl

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-2 :: Case - 7353 ::
Medical Image Database, Atlas, and Teaching File
All Cases are Peer Reviewed by an Editoral Panel