Discussion Author: Aaron Auerbach
Definition: A diffusely infiltrating astrocytoma with focal or dispersed anaplasia, and a marked proliferative potential. Anaplastic astrocytomas arise from low-grade astrocytomas, but are also diagnosed at first biopsy, without indication of a less malignant precursor lesion. They have an intrinsic tendency for malignant progression to glioblastoma.
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