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Pilomyxoid Astrocytoma (PMA), WHO Grade 2, MedPix™ : 6753 - Medical Image Database and Atlas
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More Like This ? Pilomyxoid Astrocytoma (PMA), WHO Grade 2
Topic ID: 6753 - Modified: 2009-09-22 05:53:59-04 - Created: 2005-09-28 18:30:07-04
ACR Index: 1.3

WHO Grade 2 Neoplasm of astrocytes.

Pilomyxoid astrocytoma (PMA) is a newly described variant. Previously, this tumor may have been included under the diagnosis of pilocytic astrocytoma. Pilomyxoid astrocytoma has a shorter time to recurrence, is more likely to recur; and/or cause CNS metastasis.

Related to pilocytic astrocytoma with bipolar cells arranged around vessles, in a mucoid matrix. Does not have Rosenthal fibers - which are common in pilocytics.

Pilomyxoid astrocytoma is most commonly a solid enhancing mass in the hypothalamus, and the mean age is younger (10-15 months) than for pilocytic astrocytoma(58 - 108 months).

Most common in the hypothalamus and chiasm. May occur anywhere, like pilocytic, including thalamus, brainstem, cerebellum, and spinal cord.

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These tumors were first described in the hypothalamus, and have imaging characteristics that mimic pilocytic astrocytoma.

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CME Article on pilomyxoid astrocytoma:
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Topic Contributor Credits

Topic Submitted by: James G. Smirniotopoulos, M.D. - Author Info
Affiliation: Uniformed Services University
Topic approved by: James G. Smirniotopoulos, M.D. - Editor Info
Affiliation: Uniformed Services University

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